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Anti-NPFF2 / NPFFR2 Antibody (N-Terminus)

Rabbit Anti Human Polyclonal Antibody

Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q9Y5X5
Predicted Human
Host Rabbit
Clonality Polyclonal
Calculated MW 60270 Da
Dilution IHC-P (1 - 2 µg/ml)
Additional Information
Gene ID 10886
Alias Symbol NPFFR2
Other Names NPFFR2, G protein-coupled receptor 74, HLWAR77, G-protein coupled receptor 74, Neuropeptide FF receptor 2, Neuropeptide FF 2, NPFF2, Neuropeptide FF 2 receptor, NPGPR, GPR74, NPFF-R2, NPFF2 receptor, NPGP receptor
Target/Specificity Human NPFFR2. BLAST analysis of the peptide immunogen showed no homology with other human proteins, except MFN2 (45%), MFN1 (45%).
Reconstitution & Storage Immunoaffinity purified
PrecautionsAnti-NPFF2 / NPFFR2 Antibody (N-Terminus) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Synonyms GPR74, NPFF2, NPGPR
Function Receptor for NPAF (A-18-F-amide) and NPFF (F-8-F-amide) neuropeptides, also known as morphine-modulating peptides. Can also be activated by a variety of naturally occurring or synthetic FMRF-amide like ligands. This receptor mediates its action by association with G proteins that activate a phosphatidylinositol- calcium second messenger system.
Cellular Location Cell membrane; Multi-pass membrane protein.
Tissue Location Isoform 1 is abundant in placenta. Relatively highly expressed in thymus, testis, and small intestine. Expressed at low levels in several tissues including spleen, prostate, brain, heart, ovary, colon, kidney, lung, liver and pancreas and not expressed in skeletal muscle and leukocytes. Isoform 2 expression is highest in placenta (but at relatively low level compared to isoform 1). Very low level of expression in numerous tissues including adipose tissue and many brain regions. Isoform 3 is expressed in brain and heart and, at lower levels, in kidney, liver, lung and pancreas.
Research Areas
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$ 395.00
Cat# ALS17571
(40 western blots)
Availability: 5 days
Bulk Size
Seasonal Special on Bulk Order
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