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Anti-SCN9A / Nav1.7 Antibody (Internal)

Rabbit Anti Human Polyclonal Antibody

Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q15858
Predicted Human
Host Rabbit
Clonality Polyclonal
Calculated MW 226372 Da
Dilution IHC-P (10 µg/ml)
Additional Information
Gene ID 6335
Alias Symbol SCN9A
Other Names SCN9A, ETHA, GEFSP7, Nav1.7, HNE-Na, Peripheral sodium channel 1, PN1, SFNP, Sodium channel 25, Neuroendocrine sodium channel, FEB3B, NE-NA, NENA
Target/Specificity Human SCN9A / Nav1.7. BLAST analysis of the peptide immunogen showed no homology with other human proteins, except SCN8A (71%).
Reconstitution & Storage Immunoaffinity purified
PrecautionsAnti-SCN9A / Nav1.7 Antibody (Internal) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name SCN9A
Synonyms NENA
Function Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. It is a tetrodotoxin-sensitive Na(+) channel isoform. Plays a role in pain mechanisms, especially in the development of inflammatory pain (By similarity).
Cellular Location Membrane; Multi-pass membrane protein. Note=In neurite terminals.
Tissue Location Expressed strongly in dorsal root ganglion, with only minor levels elsewhere in the body, smooth muscle cells, MTC cell line and C-cell carcinoma. Isoform 1 is expressed preferentially in the central and peripheral nervous system Isoform 2 is expressed preferentially in the dorsal root ganglion
Research Areas
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$ 395.00
Cat# ALS17583
(40 western blots)
Availability: 5 days
Bulk Size
Seasonal Special on Bulk Order
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