Anti-TSPO / PBR Antibody
Rabbit Anti Mouse Polyclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB, IHC-P |
---|---|
Primary Accession | P30536 |
Predicted | Human, Mouse, Rat |
Host | Rabbit |
Clonality | Polyclonal |
Calculated MW | 18828 Da |
Dilution | IHC-P (2.5 µg/ml), WB (0.2 µg/ml) |
Gene ID | 706 |
---|---|
Alias Symbol | TSPO |
Other Names | TSPO, BZRP, BPBS, IBP, MBR, MDRC, PBR, PBRS, PBS, PKBS, PTBR, Pk18, Translocator protein, Translocator protein (18kDa) |
Reconstitution & Storage | Affinity purified |
Precautions | Anti-TSPO / PBR Antibody is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | TSPO |
---|---|
Synonyms | BZRP, MBR |
Function | Can bind protoporphyrin IX and may play a role in the transport of porphyrins and heme (By similarity). Promotes the transport of cholesterol across mitochondrial membranes and may play a role in lipid metabolism (PubMed:24814875), but its precise physiological role is controversial. It is apparently not required for steroid hormone biosynthesis. Was initially identified as peripheral- type benzodiazepine receptor; can also bind isoquinoline carboxamides (PubMed:1847678). |
Cellular Location | Mitochondrion membrane; Multi-pass membrane protein |
Tissue Location | Found in many tissue types. Expressed at the highest levels under normal conditions in tissues that synthesize steroids. |
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