|Application ||WB, IHC-P|
|Predicted||Human, Mouse, Rat|
|Calculated MW||18828 Da|
|Dilution||IHC-P (2.5 µg/ml), WB (0.2 µg/ml)|
|Other Names||TSPO, BZRP, BPBS, IBP, MBR, MDRC, PBR, PBRS, PBS, PKBS, PTBR, Pk18, Translocator protein, Translocator protein (18kDa)|
|Reconstitution & Storage||Affinity purified|
|Precautions||Anti-TSPO / PBR Antibody is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Can bind protoporphyrin IX and may play a role in the transport of porphyrins and heme (By similarity). Promotes the transport of cholesterol across mitochondrial membranes and may play a role in lipid metabolism (PubMed:24814875), but its precise physiological role is controversial. It is apparently not required for steroid hormone biosynthesis. Was initially identified as peripheral-type benzodiazepine receptor; can also bind isoquinoline carboxamides (PubMed:1847678).|
|Cellular Location||Mitochondrion membrane; Multi-pass membrane protein|
|Tissue Location||Found in many tissue types. Expressed at the highest levels under normal conditions in tissues that synthesize steroids.|
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