|Application ||WB, IHC-P, Flo|
|Calculated MW||40716 Da|
|Dilution||Flo, IHC-P (5 µg/ml), WB|
|Other Names||CD34, CD34 molecule, CD34 antigen|
|Target/Specificity||Recognizes a class 2 epitope of the 110kD human CD34 molecule.|
|Reconstitution & Storage||Protein A purified|
|Precautions||Anti-CD34 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Possible adhesion molecule with a role in early hematopoiesis by mediating the attachment of stem cells to the bone marrow extracellular matrix or directly to stromal cells. Could act as a scaffold for the attachment of lineage specific glycans, allowing stem cells to bind to lectins expressed by stromal cells or other marrow components. Presents carbohydrate ligands to selectins.|
|Cellular Location||Membrane; Single-pass type I membrane protein|
|Tissue Location||Selectively expressed on hematopoietic progenitor cells and the small vessel endothelium of a variety of tissues|
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