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Anti-ATF6 Antibody (aa1-273, clone 70B1413.1)

Mouse Anti Human Monoclonal Antibody

     
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, IHC-P, ICC, CHIP
Primary Accession P18850
Predicted Human, Mouse, Rat, Hamster
Host Mouse
Clonality Monoclonal
Isotype IgG1,k
Clone Names 70B1413.1
Calculated MW 74585 Da
Dilution ChrIP, ICC, IHC-P (10 µg/ml), WB (1 - 3 µg/ml)
Additional Information
Gene ID 22926
Alias Symbol ATF6
Other Names ATF6, ATF6-alpha, ATF6A
Target/Specificity A partial protein containing amino acids 1-273 of human ATF6.
Reconstitution & Storage Protein G purified
PrecautionsAnti-ATF6 Antibody (aa1-273, clone 70B1413.1) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name ATF6
Function [Cyclic AMP-dependent transcription factor ATF-6 alpha]: Precursor of the transcription factor form (Processed cyclic AMP- dependent transcription factor ATF-6 alpha), which is embedded in the endoplasmic reticulum membrane (PubMed:10564271, PubMed:11158310, PubMed:11779464). Endoplasmic reticulum stress promotes processing of this form, releasing the transcription factor form that translocates into the nucleus, where it activates transcription of genes involved in the unfolded protein response (UPR) (PubMed:10564271, PubMed:11158310, PubMed:11779464).
Cellular Location Endoplasmic reticulum membrane; Single-pass type II membrane protein. Golgi apparatus membrane; Single-pass type II membrane protein. Note=Translocates from the endoplasmic reticulum to the Golgi, where it is processed.
Tissue Location Ubiquitous..
Research Areas
Citations (0)
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Discontinued
Cat# ALS17598
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