|Application ||WB, IHC-P, ICC, CHIP|
|Predicted||Human, Mouse, Rat, Hamster|
|Calculated MW||74585 Da|
|Dilution||ChrIP, ICC, IHC-P (10 µg/ml), WB (1 - 3 µg/ml)|
|Other Names||ATF6, ATF6-alpha, ATF6A|
|Target/Specificity||A partial protein containing amino acids 1-273 of human ATF6.|
|Reconstitution & Storage||Protein G purified|
|Precautions||Anti-ATF6 Antibody (aa1-273, clone 70B1413.1) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Transcription factor that acts during endoplasmic reticulum stress by activating unfolded protein response target genes. Binds DNA on the 5'-CCAC[GA]-3'half of the ER stress response element (ERSE) (5'-CCAAT-N(9)-CCAC[GA]-3') and of ERSE II (5'-ATTGG-N-CCACG-3'). Binding to ERSE requires binding of NF-Y to ERSE. Could also be involved in activation of transcription by the serum response factor.|
|Cellular Location||Endoplasmic reticulum membrane; Single-pass type II membrane protein|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
email@example.com, and receive a free "I Love Antibodies" mug.
Provided below are standard protocols that you may find useful for product applications.
If you have used an Abgent product and would like to share how it has performed, please click on the "Submit Review" button and provide the requested information. Our staff will examine and post your review and contact you if needed.
If you have any additional inquiries please email technical services at firstname.lastname@example.org.