|Application ||IHC-P, E|
|Calculated MW||84283 Da|
|Dilution||ELISA (1:200000), IHC-P (5 µg/ml)|
|Other Names||FOXM1, Forkhead box M1, Forkhead box protein M1, HFH11, HNF-3, HNF-3/fork-head homolog 11, INS-1, FOXM1B, M-phase phosphoprotein 2, MPP-2, MPHOSPH2, PIG29, TRIDENT, FKHL16, HFH-11, TGT3, Transcription factor Trident, WIN|
|Target/Specificity||Recognizes human FOXM1 isoforms 1, 2 and 3.|
|Reconstitution & Storage||Immunoaffinity purified|
|Precautions||Anti-FOXM1 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.|
|Synonyms||FKHL16, HFH11, MPP2, WIN|
|Function||Transcriptional factor regulating the expression of cell cycle genes essential for DNA replication and mitosis. Plays a role in the control of cell proliferation. Plays also a role in DNA breaks repair participating in the DNA damage checkpoint response.|
|Tissue Location||Expressed in thymus, testis, small intestine, colon followed by ovary. Appears to be expressed only in adult organs containing proliferating/cycling cells or in response to growth factors. Also expressed in epithelial cell lines derived from tumors. Not expressed in resting cells. Isoform 2 is highly expressed in testis|
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