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Anti-PDX1 Antibody (aa198-213)

Rabbit Anti Human Polyclonal Antibody

Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P52945
Predicted Human, Rabbit, Monkey
Host Rabbit
Clonality Polyclonal
Isotype IgG
Calculated MW 30771 Da
Dilution ELISA, IHC-P (5 µg/ml)
Additional Information
Gene ID 3651
Alias Symbol PDX1
Other Names PDX1, Glucose-sensitive factor, Insulin upstream factor 1, IPF1, Insulin promoter factor 1, IPF-1, IUF-1, STF-1, GSF, IDX-1, Islet/duodenum homeobox-1, IUF1, MODY4, PDX-1
Target/Specificity Recognizes human Pdx1. Species cross-reactivity: rodent.
Reconstitution & Storage Immunoaffinity purified
PrecautionsAnti-PDX1 Antibody (aa198-213) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name PDX1
Synonyms IPF1, STF1
Function Activates insulin, somatostatin, glucokinase, islet amyloid polypeptide and glucose transporter type 2 gene transcription. Particularly involved in glucose-dependent regulation of insulin gene transcription. As part of a PDX1:PBX1b:MEIS2b complex in pancreatic acinar cells is involved in the transcriptional activation of the ELA1 enhancer; the complex binds to the enhancer B element and cooperates with the transcription factor 1 complex (PTF1) bound to the enhancer A element. Binds preferentially the DNA motif 5'-[CT]TAAT[TG]-3'. During development, specifies the early pancreatic epithelium, permitting its proliferation, branching and subsequent differentiation. At adult stage, required for maintaining the hormone-producing phenotype of the beta-cell.
Cellular Location Nucleus. Cytoplasm, cytosol.
Tissue Location Duodenum and pancreas (Langerhans islet beta cells and small subsets of endocrine non-beta-cells, at low levels in acinar cells)
Research Areas
Citations (0)

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$ 395.00
Cat# ALS17605
(40 western blots)
Availability: 5 days
Bulk Size
Seasonal Special on Bulk Order
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