|Application ||WB, IHC-P|
|Predicted||Human, Mouse, Rat, Chicken, Bovine|
|Calculated MW||20159 Da|
|Dilution||IHC-P (10 µg/ml), WB (1:1000)|
|Other Names||CRYAB, Alpha-crystallin B chain, CRYA2, Crystallin, alpha B, CTPP2, Heat shock protein beta-5, HSPB5, Alpha B Crystallin, Alpha(B)-crystallin, Rosenthal fiber component, Heat-shock 20 kD like-protein|
|Reconstitution & Storage||Protein G purified|
|Precautions||Anti-CRYAB / Alpha B Crystallin Antibody (clone 1B6.1-3G4) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||May contribute to the transparency and refractive index of the lens. Has chaperone-like activity, preventing aggregation of various proteins under a wide range of stress conditions.|
|Cellular Location||Cytoplasm. Nucleus. Note=Translocates to the nucleus during heat shock and resides in sub-nuclear structures known as SC35 speckles or nuclear splicing speckles|
|Tissue Location||Lens as well as other tissues.|
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