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> home > Products > Primary Antibodies > Antibody Collections > GPCR Antibodies > Anti-HSP90B1 / GP96 / GRP94 Antibody (clone 9G10)
Anti-HSP90B1 / GP96 / GRP94 Antibody (clone 9G10)
Rat Anti Chicken Monoclonal Antibody
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Application 
| WB, IHC-P, IP, FC |
|---|---|
| Primary Accession | P14625 |
| Predicted | Human, Mouse, Rat, Rabbit, Hamster, Monkey, Pig, Chicken, Sheep, Xenopus, Bovine, Guinea Pig, Dog |
| Host | Rat |
| Clonality | Monoclonal |
| Isotype | IgG2a |
| Clone Names | 9G10 |
| Calculated MW | 92469 Da |
| Dilution | Flo (1:100), IHC-P (10 µg/ml), IP (1:100), WB (1:1000) |
| Gene ID | 7184 |
|---|---|
| Alias Symbol | HSP90B1 |
| Other Names | HSP90B1, ECGP, Endoplasmin, gp96 homolog, gp96, GRP-94, GRP94, Tumor rejection antigen 1, TRA1 |
| Reconstitution & Storage | Protein G purified |
| Precautions | Anti-HSP90B1 / GP96 / GRP94 Antibody (clone 9G10) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | HSP90B1 (HGNC:12028) |
|---|---|
| Synonyms | GRP94, TRA1 |
| Function | Molecular chaperone that functions in the processing and transport of secreted proteins (By similarity). When associated with CNPY3, required for proper folding of Toll-like receptors (By similarity). Functions in endoplasmic reticulum associated degradation (ERAD) (PubMed:18264092). Has ATPase activity (By similarity). May participate in the unfolding of cytosolic leaderless cargos (lacking the secretion signal sequence) such as the interleukin 1/IL-1 to facilitate their translocation into the ERGIC (endoplasmic reticulum- Golgi intermediate compartment) and secretion; the translocation process is mediated by the cargo receptor TMED10 (PubMed:32272059). |
| Cellular Location | Endoplasmic reticulum lumen. Sarcoplasmic reticulum lumen {ECO:0000250|UniProtKB:P41148}. Melanosome Note=Identified by mass spectrometry in melanosome fractions from stage I to stage IV. |
Research Areas
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Application Protocols
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