|Application ||WB, IHC-P, IF, E|
|Predicted||Human, Mouse, Rat|
|Calculated MW||23400 Da|
|Dilution||ELISA, IF (10 µg/ml), IHC-P (5 µg/ml), WB|
|Other Names||RRAS2, Ras-like protein TC21, Ras-related protein R-Ras2, TC21, Teratocarcinoma oncogene|
|Reconstitution & Storage||Protein A purified|
|Precautions||Anti-TC21 / RRAS2 Antibody (clone 2D3-4B8) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||It is a plasma membrane-associated GTP-binding protein with GTPase activity. Might transduce growth inhibitory signals across the cell membrane, exerting its effect through an effector shared with the Ras proteins but in an antagonistic fashion.|
|Cellular Location||Cell membrane; Lipid-anchor; Cytoplasmic side. Note=Inner surface of plasma membrane possibly with attachment requiring acylation of the C-terminal cysteine (By similarity with RAS)|
|Tissue Location||Ubiquitously present in all tissues examined, with the highest levels in heart, placenta, and skeletal muscle Moderate levels in lung and liver; low levels in brain, kidney, and pancreas.|
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