Anti-MCF2L / DBS Antibody (clone 1D11)
Mouse Anti Human Monoclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB, IHC-P, E |
---|---|
Primary Accession | O15068 |
Predicted | Human |
Host | Mouse |
Clonality | Monoclonal |
Isotype | IgG1,k |
Clone Names | 1D11 |
Calculated MW | 128109 Da |
Dilution | ELISA, IHC-P (5 µg/ml), WB |
Gene ID | 23263 |
---|---|
Alias Symbol | MCF2L |
Other Names | MCF2L, ARHGEF14, DBS, KIAA0362, OST, DBLs big sister |
Reconstitution & Storage | Protein A purified |
Precautions | Anti-MCF2L / DBS Antibody (clone 1D11) is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | MCF2L |
---|---|
Synonyms | KIAA0362, OST {ECO:0000303|PubMed:151576 |
Function | Guanine nucleotide exchange factor that catalyzes guanine nucleotide exchange on RHOA and CDC42, and thereby contributes to the regulation of RHOA and CDC42 signaling pathways (By similarity). Seems to lack activity with RAC1. Becomes activated and highly tumorigenic by truncation of the N-terminus (By similarity). Isoform 5 activates CDC42 (PubMed:15157669). |
Cellular Location | [Isoform 5]: Cytoplasm. Cell membrane; Peripheral membrane protein; Cytoplasmic side Cytoplasm {ECO:0000250|UniProtKB:Q64096}. Cell membrane {ECO:0000250|UniProtKB:Q64096}; Peripheral membrane protein {ECO:0000250|UniProtKB:Q64096}; Cytoplasmic side {ECO:0000250|UniProtKB:Q64096} |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
info@abcepta.com, and receive a free "I Love Antibodies" mug.
Provided below are standard protocols that you may find useful for product applications.
If you have used an Abcepta product and would like to share how it has performed, please click on the "Submit Review" button and provide the requested information. Our staff will examine and post your review and contact you if needed.
If you have any additional inquiries please email technical services at tech@abcepta.com.