Anti-EPSTI1 Antibody (clone 2A8)
Mouse Anti Human Monoclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB, IHC-P, E |
---|---|
Primary Accession | Q96J88 |
Predicted | Human |
Host | Mouse |
Clonality | Monoclonal |
Isotype | IgG1,k |
Clone Names | 2A8 |
Calculated MW | 36793 Da |
Dilution | ELISA, IHC-P (5 µg/ml), WB |
Gene ID | 94240 |
---|---|
Alias Symbol | EPSTI1 |
Other Names | EPSTI1, BRESI1 |
Reconstitution & Storage | Protein A purified |
Precautions | Anti-EPSTI1 Antibody (clone 2A8) is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | EPSTI1 |
---|---|
Function | Plays a role in M1 macrophage polarization and is required for the proper regulation of gene expression during M1 versus M2 macrophage differentiation (By similarity). Might play a role in RELA/p65 and STAT1 phosphorylation and nuclear localization upon activation of macrophages (By similarity). |
Tissue Location | Highly expressed in placenta, small intestine, spleen, kidney, thymus, liver, salivary gland and testes. Weakly expressed in breast, skeletal muscle and colon. Highly expressed in breast cancer upon interaction between tumor cells and stromal cells in vitro. Expressed in blood mononuclear cells from patients with systemic lupus erythematosus (SLE). |
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