|Application ||WB, IHC-P, IP|
|Predicted||Human, Mouse, Rat, Rabbit, Monkey, Pig, Dog, Cat|
|Calculated MW||37337 Da|
|Dilution||IHC-P (5 µg/ml), IP (10 - 20 µg/ml), WB (0.5 - 4 µg/ml)|
|Other Names||MCL1, BCL2L3, Bcl-2-like protein 3, Bcl-2-related protein EAT/mcl1, Bcl2-L-3, MCL1S, MCL1L, Myeloid cell leukemia ES, MCL 1, MCL1-ES, TM, EAT, Mcl-1|
|Reconstitution & Storage||Affinity purified|
|Precautions||Anti-MCL1 / MCL 1 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Involved in the regulation of apoptosis versus cell survival, and in the maintenance of viability but not of proliferation. Mediates its effects by interactions with a number of other regulators of apoptosis. Isoform 1 inhibits apoptosis. Isoform 2 promotes apoptosis.|
|Cellular Location||Membrane; Single-pass membrane protein. Cytoplasm. Mitochondrion. Nucleus, nucleoplasm. Note=Cytoplasmic, associated with mitochondria|
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