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Anti-TLR9 Antibody (N-Terminus)

Goat Anti Mouse Polyclonal Antibody

Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q9NR96
Predicted Mouse, Hamster
Host Goat
Clonality Polyclonal
Calculated MW 115860 Da
Dilution ELISA, ICC (1:200), IHC-P (2.5 µg/ml), WB
Additional Information
Gene ID 54106
Alias Symbol TLR9
Other Names TLR9, CD289, CD289 antigen, Scri2a, Toll-like receptor 9
Target/Specificity Peptide sequence is <50 % identical to other mouse TLR receptors in this region. The antibody recognizes mouse TLR9 and human TLR9.
Reconstitution & Storage Immunoaffinity purified
PrecautionsAnti-TLR9 Antibody (N-Terminus) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name TLR9
Function Key component of innate and adaptive immunity. TLRs (Toll-like receptors) control host immune response against pathogens through recognition of molecular patterns specific to microorganisms. TLR9 is a nucleotide-sensing TLR which is activated by unmethylated cytidine-phosphate-guanosine (CpG) dinucleotides. Acts via MYD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. Controls lymphocyte response to Helicobacter infection.
Cellular Location Endoplasmic reticulum membrane; Single-pass type I membrane protein Endosome. Lysosome. Cytoplasmic vesicle, phagosome. Note=Relocalizes from endoplasmic reticulum to endosome and lysosome upon stimulation with agonist.
Tissue Location Highly expressed in spleen, lymph node, tonsil and peripheral blood leukocytes, especially in plasmacytoid pre- dendritic cells. Levels are much lower in monocytes and CD11c+ immature dendritic cells. Also detected in lung and liver
Research Areas
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$ 395.00
Cat# ALS17665
(40 western blots)
Availability: 5 days
Bulk Size
Seasonal Special on Bulk Order
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