|Application ||WB, IHC-P, E|
|Calculated MW||39318 Da|
|Dilution||ELISA, IHC-P (5 µg/ml), WB (1:500 - 1:1000)|
|Other Names||MAP2K3, MAPKK 3, MAPKK3, PRKMK3, SAPK kinase 2, SAPKK-2, SAPKK2, SKK2, MAP kinase kinase 3, MEK 3, MEK3, MKK3, MAPK/ERK kinase 3|
|Reconstitution & Storage||Protein A purified|
|Precautions||Anti-MAP2K3 / MEK3 / MKK3 Antibody (clone 1D10) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Synonyms||MEK3, MKK3, PRKMK3, SKK2|
|Function||Dual specificity kinase. Is activated by cytokines and environmental stress in vivo. Catalyzes the concomitant phosphorylation of a threonine and a tyrosine residue in the MAP kinase p38. Part of a signaling cascade that begins with the activation of the adrenergic receptor ADRA1B and leads to the activation of MAPK14.|
|Tissue Location||Abundant expression is seen in the skeletal muscle. It is also widely expressed in other tissues|
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