|Application ||WB, IHC-P, IF, E|
|Calculated MW||83239 Da|
|Dilution||ELISA, IF (10 µg/ml), IHC-P (5 µg/ml), WB (1:500 - 1:1000)|
|Other Names||RPS6KA2, HU-2, MAPKAPK-1c, MAPKAPK1C, p90 ribosomal s6 kinase 3, p90RSK2, Pp90RSK3, Ribosomal S6 kinase 3, RSK-3, S6K-alpha, p90-RSK3, RSK, RSK3, S6K-alpha-2, S6K-alpha2, MAPKAP kinase 1c, p90-RSK 2|
|Reconstitution & Storage||Protein A purified|
|Precautions||Anti-RPS6KA2 / RSK3 Antibody (clone 1F6) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Serine/threonine-protein kinase that acts downstream of ERK (MAPK1/ERK2 and MAPK3/ERK1) signaling and mediates mitogenic and stress-induced activation of transcription factors, regulates translation, and mediates cellular proliferation, survival, and differentiation. May function as tumor suppressor in epithelial ovarian cancer cells.|
|Cellular Location||Nucleus. Cytoplasm|
|Tissue Location||Widely expressed with higher expression in lung, skeletal muscle, brain, uterus, ovary, thyroid and prostate|
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