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> home > Products > Primary Antibodies > Antibody Collections > GPCR Antibodies > Anti-HELO1 / ELOVL5 Antibody (N-Terminus)
Anti-HELO1 / ELOVL5 Antibody (N-Terminus)
Rabbit Anti Human Polyclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| IHC-P |
|---|---|
| Primary Accession | Q9NYP7 |
| Predicted | Human, Monkey, Chicken |
| Host | Rabbit |
| Clonality | Polyclonal |
| Calculated MW | 35293 Da |
| Dilution | IHC-P (10 - 15 µg/ml) |
| Gene ID | 60481 |
|---|---|
| Alias Symbol | ELOVL5 |
| Other Names | ELOVL5, ELOVL FA elongase 5, ELOVL fatty acid elongase 5, Fatty acid elongase 1, RP3-483K16.1, DJ483K16.1, HELO1 |
| Target/Specificity | Human ELOVL5. BLAST analysis of the peptide immunogen showed no homology with other human proteins. |
| Reconstitution & Storage | Immunoaffinity purified |
| Precautions | Anti-HELO1 / ELOVL5 Antibody (N-Terminus) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | ELOVL5 {ECO:0000255|HAMAP-Rule:MF_03205} |
|---|---|
| Synonyms | ELOVL2 |
| Function | Catalyzes the first and rate-limiting reaction of the four reactions that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids (VLCFAs) per cycle. Condensing enzyme that acts specifically toward polyunsaturated acyl-CoA with the higher activity toward C18:3(n-6) acyl-CoA. May participate in the production of monounsaturated and of polyunsaturated VLCFAs of different chain lengths that are involved in multiple biological processes as precursors of membrane lipids and lipid mediators (By similarity) (PubMed:10970790, PubMed:20937905). In conditions where the essential linoleic and alpha linoleic fatty acids are lacking it is also involved in the synthesis of Mead acid from oleic acid (By similarity). |
| Cellular Location | Endoplasmic reticulum membrane {ECO:0000255|HAMAP-Rule:MF_03205, ECO:0000269|PubMed:20937905}; Multi- pass membrane protein {ECO:0000255|HAMAP-Rule:MF_03205}. Cell projection, dendrite {ECO:0000255|HAMAP-Rule:MF_03205, ECO:0000269|PubMed:25065913}. Note=In Purkinje cells, the protein localizes to the soma and proximal portion of the dendritic tree {ECO:0000255|HAMAP-Rule:MF_03205, ECO:0000269|PubMed:25065913} |
| Tissue Location | Ubiquitous. Highly expressed in the adrenal gland and testis. Weakly expressed in prostate, lung and brain. Expressed in the cerebellum. |
Research Areas
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$ 467.50
Cat# ALS17680
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