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Anti-CD71 / Transferrin Receptor Antibody (clone 1E6)

Mouse Anti Human Monoclonal Antibody

Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P02786
Predicted Human
Host Mouse
Clonality Monoclonal
Isotype IgG2b,k
Clone Names 1E6
Calculated MW 84871 Da
Dilution ELISA, IHC-P (5 µg/ml), WB (1:500 - 1:1000)
Additional Information
Gene ID 7037
Alias Symbol TFRC
Other Names TFRC, CD71, TFR1, TRFR, TFR, TR, CD71 antigen, p90, T9, Transferrin receptor, Transferrin receptor protein 1
Target/Specificity Human Transferrin Receptor
Reconstitution & Storage Protein A purified
PrecautionsAnti-CD71 / Transferrin Receptor Antibody (clone 1E6) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Function Cellular uptake of iron occurs via receptor-mediated endocytosis of ligand-occupied transferrin receptor into specialized endosomes. Endosomal acidification leads to iron release. The apotransferrin-receptor complex is then recycled to the cell surface with a return to neutral pH and the concomitant loss of affinity of apotransferrin for its receptor. Transferrin receptor is necessary for development of erythrocytes and the nervous system (By similarity). A second ligand, the heditary hemochromatosis protein HFE, competes for binding with transferrin for an overlapping C-terminal binding site.
Cellular Location Cell membrane; Single-pass type II membrane protein. Melanosome. Note=Identified by mass spectrometry in melanosome fractions from stage I to stage IV
Research Areas
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$ 450.00
Cat# ALS17689
(40 western blots)
Availability: 5 days
Bulk Size
Seasonal Special on Bulk Order
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