|Application ||WB, IHC-P, E, IP|
|Calculated MW||61807 Da|
|Dilution||ELISA, IHC-P (5 µg/ml), IP, WB (1:500 - 1:1000)|
|Other Names||CES2, Carboxylesterase 2, CE-2, CES2A1, Cocaine esterase, Esterase, ICE, HCE-2, PCE-2|
|Reconstitution & Storage||Protein A purified|
|Precautions||Anti-CES2 / Esterase Antibody (clone 4F12) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Involved in the detoxification of xenobiotics and in the activation of ester and amide prodrugs. Shows high catalytic efficiency for hydrolysis of cocaine, 4-methylumbelliferyl acetate, heroin and 6-monoacetylmorphine.|
|Cellular Location||Endoplasmic reticulum lumen.|
|Tissue Location||Preferentially expressed in intestine with moderate expression in liver. Within the intestine, highest expression is found in small intestine with lower expression in colon and rectum.|
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