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> home > Products > Primary Antibodies > Antibody Collections > GPCR Antibodies > Anti-CLEC2D / OCIL / LLT1 Antibody (clone 4C7)
Anti-CLEC2D / OCIL / LLT1 Antibody (clone 4C7)
Mouse Anti Human Monoclonal Antibody
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Application 
| WB, IHC-P, E |
|---|---|
| Primary Accession | Q9UHP7 |
| Predicted | Human |
| Host | Mouse |
| Clonality | Monoclonal |
| Isotype | IgG1,k |
| Clone Names | 4C7 |
| Calculated MW | 21849 Da |
| Dilution | ELISA, IHC-P (3 - 5 µg/ml), WB (1:500 - 1:1000) |
| Gene ID | 29121 |
|---|---|
| Alias Symbol | CLEC2D |
| Other Names | CLEC2D, C-type lectin related f, CLAX, LLT-1, LLT1, OCIL, Osteoclast inhibitory lectin, Lectin-like NK cell receptor, Lectin-like transcript 1 |
| Target/Specificity | Human CLEC2D |
| Reconstitution & Storage | Protein A purified |
| Precautions | Anti-CLEC2D / OCIL / LLT1 Antibody (clone 4C7) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | CLEC2D |
|---|---|
| Synonyms | CLAX, LLT1, OCIL |
| Function | Receptor for KLRB1 that protects target cells against natural killer cell-mediated lysis (PubMed:20843815, PubMed:16339513). Inhibits osteoclast formation (PubMed:14753741, PubMed:15123656). Inhibits bone resorption (PubMed:14753741). Modulates the release of interferon-gamma (PubMed:15104121). Binds high molecular weight sulfated glycosaminoglycans (PubMed:15123656). |
| Cellular Location | Cell membrane; Single-pass type II membrane protein [Isoform 4]: Endoplasmic reticulum |
| Tissue Location | Detected in peripheral blood leukocytes, osteoblasts, lymph node, thymus and spleen. Isoform 1, isoform 2 and isoform 4 are expressed in T- and B-lymphocytes, and at lower levels in NK cells. They are also expressed in B-cell lines and LPS-matured monocyte-derived dendritic cells. |
Research Areas
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Application Protocols
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$ 533.50
Cat# ALS17715
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