|Application ||WB, IHC-P, IF, E|
|Calculated MW||23565 Da|
|Dilution||ELISA, IF (10 µg/ml), IHC-P (1 - 5 µg/ml), WB (1:500 - 1:1000)|
|Other Names||GMNN, Geminin|
|Reconstitution & Storage||Protein A purified|
|Precautions||Anti-Geminin Antibody (clone 1A8) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Inhibits DNA replication by preventing the incorporation of MCM complex into pre-replication complex (pre-RC). It is degraded during the mitotic phase of the cell cycle. Its destruction at the metaphase-anaphase transition permits replication in the succeeding cell cycle.|
|Cellular Location||Cytoplasm. Nucleus. Note=Mainly cytoplasmic but can be relocalized to the nucleus|
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