|Application ||WB, IHC-P, E|
|Calculated MW||105848 Da|
|Dilution||ELISA, IHC-P (5 µg/ml), WB|
|Other Names||PTPRN, ICA512, IA2, ICA 512, Islet antigen 2, Islet cell antigen 2, Islet cell autoantigen 3, IA-2, Ia-2 antigen, ICA3, PTP-NP-2, PTP IA-2, R-PTP-N, IA-2/PTP, Islet cell antigen 512|
|Reconstitution & Storage||Protein A purified|
|Precautions||Anti-PTPRN / IA-2 Antibody (clone 8E3) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Implicated in neuroendocrine secretory processes. May be involved in processes specific for neurosecretory granules, such as their biogenesis, trafficking or regulated exocytosis or may have a general role in neuroendocrine functions. Seems to lack intrinsic enzyme activity. May play a role in the regulation of secretory granules via its interaction with SNTB2.|
|Cellular Location||Membrane; Single-pass type I membrane protein. Note=Neuroendocrine secretory granules|
|Tissue Location||Expression is restricted to neuroendocrine cells. Found in pancreas, brain and pituitary|
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