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Anti-ING3 Antibody (clone 2E9)

Mouse Anti Human Monoclonal Antibody

     
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, IHC-P, E
Primary Accession Q9NXR8
Predicted Human
Host Mouse
Clonality Monoclonal
Isotype IgG2a,k
Clone Names 2E9
Calculated MW 46743 Da
Dilution ELISA, IHC-P (5 µg/ml), WB
Additional Information
Gene ID 54556
Alias Symbol ING3
Other Names ING3, p47ING3, Inhibitor of growth protein 3, MEAF4, Eaf4, p47
Target/Specificity Human ING3
Reconstitution & Storage Protein A purified
PrecautionsAnti-ING3 Antibody (clone 2E9) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name ING3
Function Component of the NuA4 histone acetyltransferase (HAT) complex which is involved in transcriptional activation of select genes principally by acetylation of nucleosomal histones H4 and H2A. This modification may both alter nucleosome - DNA interactions and promote interaction of the modified histones with other proteins which positively regulate transcription. This complex may be required for the activation of transcriptional programs associated with oncogene and proto-oncogene mediated growth induction, tumor suppressor mediated growth arrest and replicative senescence, apoptosis, and DNA repair. NuA4 may also play a direct role in DNA repair when directly recruited to sites of DNA damage. Component of a SWR1-like complex that specifically mediates the removal of histone H2A.Z/H2AZ1 from the nucleosome.
Cellular Location Nucleus.
Tissue Location Expressed in brain, heart, kidney, liver, lung, ovaries, placenta, prostate, skeletal muscle, small intestine, spleen, testis and thymus
Research Areas
Citations (0)
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$ 533.50
Cat# ALS17722
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