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Anti-MPO / Myeloperoxidase Antibody
Rabbit Anti Human Polyclonal Antibody
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- BACKGROUND
Application 
| IHC-P |
|---|---|
| Primary Accession | P05164 |
| Predicted | Human, Mouse, Rat |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Calculated MW | 83869 Da |
| Dilution | IHC-P (1:100) |
| Gene ID | 4353 |
|---|---|
| Alias Symbol | MPO |
| Other Names | MPO, Myeloperoxidase precursor, Myeloperoxidase |
| Target/Specificity | Recognizes human myeloperoxidase (MPO). |
| Reconstitution & Storage | Purified |
| Precautions | Anti-MPO / Myeloperoxidase Antibody is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | MPO (HGNC:7218) |
|---|---|
| Function | Part of the host defense system of polymorphonuclear leukocytes. It is responsible for microbicidal activity against a wide range of organisms. In the stimulated PMN, MPO catalyzes the production of hypohalous acids, primarily hypochlorous acid in physiologic situations, and other toxic intermediates that greatly enhance PMN microbicidal activity (PubMed:9922160). Mediates the proteolytic cleavage of alpha-1-microglobulin to form t-alpha-1-microglobulin, which potently inhibits oxidation of low-density lipoprotein particles and limits vascular damage (PubMed:25698971). |
| Cellular Location | Lysosome. |
Research Areas
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