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Anti-ERO1A / ERO1L Antibody (aa105-118)

Goat Anti Human Polyclonal Antibody

Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q96HE7
Predicted Human, Rabbit, Dog
Host Goat
Clonality Polyclonal
Calculated MW 54393 Da
Dilution ELISA (1:32000), IHC-P (5 µg/ml), WB (0.1 - 0.3 µg/ml)
Additional Information
Gene ID 30001
Alias Symbol ERO1L
Other Names ERO1L, ERO1-like (S. cerevisiae), ERO1 (S. cerevisiae)-like, ERO1A, ERO1-alpha, ERO1-L-alpha, ERO1-like protein alpha, Oxidoreductin-1-L-alpha, ERO1-L
Target/Specificity Human ERO1L.
Reconstitution & Storage Immunoaffinity purified
PrecautionsAnti-ERO1A / ERO1L Antibody (aa105-118) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name ERO1L
Function Oxidoreductase involved in disulfide bond formation in the endoplasmic reticulum. Efficiently reoxidizes P4HB/PDI, the enzyme catalyzing protein disulfide formation, in order to allow P4HB to sustain additional rounds of disulfide formation. Following P4HB reoxidation, passes its electrons to molecular oxygen via FAD, leading to the production of reactive oxygen species (ROS) in the cell. Required for the proper folding of immunoglobulins. Involved in the release of the unfolded cholera toxin from reduced P4HB/PDI in case of infection by V.cholerae, thereby playing a role in retrotranslocation of the toxin. Plays an important role in ER stress-induced, CHOP-dependent apoptosis by activating the inositol 1,4,5-trisphosphate receptor IP3R1.
Cellular Location Endoplasmic reticulum membrane; Peripheral membrane protein; Lumenal side Note=The association with ERP44 is essential for its retention in the endoplasmic reticulum
Tissue Location Widely expressed at low level. Expressed at high level in upper digestive tract. Highly expressed in esophagus. Weakly expressed in stomach and duodenum
Research Areas
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$ 395.00
Cat# ALS17728
(40 western blots)
Availability: 5 days
Bulk Size
Seasonal Special on Bulk Order
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