|Application ||WB, IHC-P, E|
|Calculated MW||39751 Da|
|Dilution||ELISA, IHC-P (10 µg/ml), WB (1:1000)|
|Other Names||IST1, CRS1, HIST1, IST1 homolog, KIAA0174, OLC1, Increased sodium tolerance-1, SCS, Overexpressed in lung cancer 1, TWACS3|
|Target/Specificity||Anti-hIST1 recognizes hIST1 expression in H520 whole cell lysate.|
|Reconstitution & Storage||Affinity purified|
|Precautions||Anti-IST1 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Proposed to be involved in specific functions of the ESCRT machinery. Is required for efficient abscission during cytokinesis, but not for HIV-1 budding. The involvement in the MVB pathway is not established. Involved in recruiting VPS4A and/or VPS4B to the midbody of dividing cells.|
|Cellular Location||Cytoplasmic vesicle Note=Localizes to the midbody of dividing cells|
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