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Anti-TNFRSF1B / TNFR2 Antibody

Rabbit Anti Human Polyclonal Antibody

     
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, IHC-P, E, Neut
Primary Accession P20333
Predicted Human
Host Rabbit
Clonality Polyclonal
Isotype IgG
Calculated MW 48291 Da
Dilution ELISA (0.5 - 2 µg/ml), IHC-P (5 µg/ml), Neut (15 - 20 µg/ml), WB (0.1 - 0.2 µg/ml)
Additional Information
Gene ID 7133
Alias Symbol TNFRSF1B
Other Names TNFRSF1B, CD120b antigen, CD120b, Etanercept, p75 TNF receptor, Soluble TNFR1B variant 1, TNFBR, Tumor necrosis factor receptor, TNF-R-II, TNF-R75, TNFR2, p75TNFR, p80 TNF-alpha receptor, TBPII, TNF-R2, TNFR80, TNF-RII, TNFR-II, TNFR1B
Target/Specificity Human sTNF Receptor-II
Reconstitution & Storage Immunoaffinity purified
PrecautionsAnti-TNFRSF1B / TNFR2 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name TNFRSF1B
Synonyms TNFBR, TNFR2
Function Receptor with high affinity for TNFSF2/TNF-alpha and approximately 5-fold lower affinity for homotrimeric TNFSF1/lymphotoxin-alpha. The TRAF1/TRAF2 complex recruits the apoptotic suppressors BIRC2 and BIRC3 to TNFRSF1B/TNFR2. This receptor mediates most of the metabolic effects of TNF-alpha. Isoform 2 blocks TNF-alpha-induced apoptosis, which suggests that it regulates TNF-alpha function by antagonizing its biological activity.
Cellular Location Isoform 1: Cell membrane; Single-pass type I membrane protein Tumor necrosis factor-binding protein 2: Secreted
Research Areas
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$ 395.00
Cat# ALS17735
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