|Application ||WB, IHC-P, E, Neut|
|Calculated MW||38091 Da|
|Dilution||ELISA (0.5 - 2 µg/ml), IHC-P (5 µg/ml), Neut (6 - 9 µg/ml), WB|
|Other Names||CTGF, CCN family member 2, CCN2, IGFBP8, IGF-binding protein 8, NOV2, HCS24, IBP-8, IGFBP-8|
|Reconstitution & Storage||Immunoaffinity purified|
|Precautions||Anti-CTGF Antibody is for research use only and not for use in diagnostic or therapeutic procedures.|
|Synonyms||CCN2, HCS24, IGFBP8|
|Function||Major connective tissue mitoattractant secreted by vascular endothelial cells. Promotes proliferation and differentiation of chondrocytes. Mediates heparin- and divalent cation-dependent cell adhesion in many cell types including fibroblasts, myofibroblasts, endothelial and epithelial cells. Enhances fibroblast growth factor-induced DNA synthesis.|
|Cellular Location||Secreted, extracellular space, extracellular matrix. Secreted|
|Tissue Location||Expressed in bone marrow and thymic cells. Also expressed one of two Wilms tumors tested|
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