|Application ||WB, IHC-P, IF, E, IP|
|Calculated MW||90584 Da|
|Dilution||ELISA, IF, IHC-P (10 µg/ml), IP, WB|
|Other Names||HNRNPU, HnRNP U, HNRPU, p120, p120 nuclear protein, SAFA, Scaffold attachment factor A, U21.1, Pp120, SAF-A|
|Target/Specificity||Human hnRNP-U. Detects a band of approximately 120 kD. It cross reacts with monkey|
|Reconstitution & Storage||Protein A purified|
|Precautions||Anti-HnRNP U Antibody (clone 3G6) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Synonyms||HNRPU, SAFA, U21.1|
|Function||Component of the CRD-mediated complex that promotes MYC mRNA stabilization. Binds to pre-mRNA. Has high affinity for scaffold-attached region (SAR) DNA. Binds to double- and single- stranded DNA and RNA. Plays a role in the circadian regulation of the core clock component ARNTL/BMAL1 transcription (By similarity).|
|Cellular Location||Nucleus. Cytoplasm. Cell surface. Note=Localized in cytoplasmic mRNP granules containing untranslated mRNAs. Component of ribonucleosomes.|
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