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>   home   >   Products   >   Primary Antibodies   >   Antibody Collections   >   GPCR Antibodies   >   Anti-MFGE8 /Lactadherin Antibody (clone EDM45)   

Anti-MFGE8 /Lactadherin Antibody (clone EDM45)

Mouse Anti Human Monoclonal Antibody

Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q08431
Predicted Human
Host Mouse
Clonality Monoclonal
Isotype IgG1,k
Clone Names EDM45
Calculated MW 43123 Da
Dilution IF, IHC-P (10 µg/ml), IP (0.5 - 1 µg/ml), WB (0.5 - 1 µg/ml)
Additional Information
Gene ID 4240
Alias Symbol MFGE8
Other Names MFGE8, Breast epithelial antigen BA46, EDIL1, HP47, Lactadherin, Medin, MFGM, Milk fat globule-EGF factor 8, HsT19888, OAcGD3S, SPAG10, Sperm associated antigen 10, MFG-E8, SED1, Sperm surface protein hP47, BA46, HMFG
Reconstitution & Storage Protein G purified
PrecautionsAnti-MFGE8 /Lactadherin Antibody (clone EDM45) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name MFGE8
Function Plays an important role in the maintenance of intestinal epithelial homeostasis and the promotion of mucosal healing. Promotes VEGF-dependent neovascularization (By similarity). Contributes to phagocytic removal of apoptotic cells in many tissues. Specific ligand for the alpha-v/beta-3 and alpha-v/beta-5 receptors. Also binds to phosphatidylserine-enriched cell surfaces in a receptor-independent manner. Zona pellucida-binding protein which may play a role in gamete interaction. Binds specifically to rotavirus and inhibits its replication.
Cellular Location Membrane; Peripheral membrane protein Secreted
Tissue Location Mammary epithelial cell surfaces and aortic media. Overexpressed in several carcinomas
Research Areas
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$ 450.00
Cat# ALS17800
(40 western blots)
Availability: 5 days
Bulk Size
Seasonal Special on Bulk Order
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