|Application ||WB, IHC-P, E|
|Calculated MW||102357 Da|
|Dilution||ELISA, IHC-P (10 µg/ml), WB|
|Other Names||ESYT2, CHR2SYT, Chr2 synaptotagmin, FAM62B, KIAA1228, E-Syt2, Extended synaptotagmin-2|
|Reconstitution & Storage||Protein A purified|
|Precautions||Anti-ESYT2 / E-Syt2 Antibody (clone 1E10) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Tethers the endoplasmic reticulum to the cell membrane and promotes the formation of appositions between the endoplasmic reticulum and the cell membrane. Binds glycerophospholipids in a barrel-like domain and may play a role in cellular lipid transport. Plays a role in FGF signaling via its role in the rapid internalization of FGFR1 that has been activated by FGF1 binding; this occurs most likely via the AP-2 complex.|
|Cellular Location||Cell membrane; Peripheral membrane protein. Endoplasmic reticulum membrane; Multi-pass membrane protein Note=Detected at sites of contact between the endoplasmic reticulum membrane and the cell membrane. Recruited to the cell membrane via the third C2 domain|
|Tissue Location||Widely expressed with high level in cerebellum.|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
email@example.com, and receive a free "I Love Antibodies" mug.
Provided below are standard protocols that you may find useful for product applications.
If you have used an Abgent product and would like to share how it has performed, please click on the "Submit Review" button and provide the requested information. Our staff will examine and post your review and contact you if needed.
If you have any additional inquiries please email technical services at firstname.lastname@example.org.