|Application ||WB, IHC-P, E|
|Calculated MW||25913 Da|
|Dilution||ELISA (1:32000), IHC-P (3.75 µg/ml), WB (0.1 - 0.3 µg/ml)|
|Other Names||DCXR, Carbonyl reductase 2, DCR, HCR2, HCRII, L-xylulose reductase, XR, Carbonyl reductase II, KIDCR, Kidney dicarbonyl reductase, p34H, SDR20C1, Sperm surface protein P34H|
|Reconstitution & Storage||Immunoaffinity purified|
|Precautions||Anti-DCXR Antibody (aa232-244) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Catalyzes the NADPH-dependent reduction of several pentoses, tetroses, trioses, alpha-dicarbonyl compounds and L- xylulose. Participates in the uronate cycle of glucose metabolism. May play a role in the water absorption and cellular osmoregulation in the proximal renal tubules by producing xylitol, an osmolyte, thereby preventing osmolytic stress from occurring in the renal tubules.|
|Cellular Location||Membrane; Peripheral membrane protein. Note=Probably recruited to membranes via an interaction with phosphatidylinositol.|
|Tissue Location||Highly expressed in kidney, liver and epididymis. In the epididymis, it is mainly expressed in the proximal and distal sections of the corpus region. Weakly or not expressed in brain, lung, heart, spleen and testis|
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