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Anti-PPP2R4 Antibody (aa347-358)

Goat Anti Human Polyclonal Antibody

Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q15257
Predicted Human, Mouse, Rat, Rabbit, Hamster, Monkey
Host Goat
Clonality Polyclonal
Calculated MW 40668 Da
Dilution ELISA (1:32000), IHC-P (3.75 µg/ml), WB (0.5 - 2 µg/ml)
Additional Information
Gene ID 5524
Alias Symbol PPP2R4
Other Names PPP2R4, PP2A phosphatase activator, PP2A subunit B isoform PR53, PTPA, PP2A, PP2A, subunit B, PR53 isoform, PR53
Target/Specificity Human PPP2R4. This antibody is expected to recognize all reported isoforms (NP_821068.1; NP_066954.2; NP_821070.1). Reported variants NP_066954.2 and NP_821067.1 represent identical protein.
Reconstitution & Storage Immunoaffinity purified
PrecautionsAnti-PPP2R4 Antibody (aa347-358) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name PPP2R4
Synonyms PTPA
Function PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. Acts as a regulatory subunit for serine/threonine- protein phosphatase 2A (PP2A) modulating its activity or substrate specificity, probably by inducing a conformational change in the catalytic subunit, a proposed direct target of the PPIase. Can reactivate inactive phosphatase PP2A-phosphatase methylesterase complexes (PP2A(i)) in presence of ATP and Mg(2+) (By similarity). Reversibly stimulates the variable phosphotyrosyl phosphatase activity of PP2A core heterodimer PP2A(D) in presence of ATP and Mg(2+) (in vitro). The phosphotyrosyl phosphatase activity is dependent of an ATPase activity of the PP2A(D):PPP2R4 complex. Is involved in apoptosis; the function appears to be independent from PP2A.
Cellular Location Cytoplasm. Nucleus
Tissue Location Widely expressed.
Research Areas
Citations (0)

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$ 395.00
Cat# ALS17812
(40 western blots)
Availability: 5 days
Bulk Size
Seasonal Special on Bulk Order
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