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Anti-CTSC / Cathepsin C / JP Antibody

Mouse Anti Human Monoclonal Antibody

     
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, IHC-P, E
Primary Accession P53634
Predicted Human
Host Mouse
Clonality Monoclonal
Isotype IgG2b
Calculated MW 51854 Da
Dilution ELISA, IHC-P (1:50), WB (1:1000)
Additional Information
Gene ID 1075
Alias Symbol CTSC
Other Names CTSC, Cathepsin J, Dipeptidyl peptidase 1, Dipeptidyl peptidase I, DPP-I, Dipeptidyl transferase, Dipeptidyl-peptidase I, CPPI, DPPI, DPP1, HMS, JP, PDON1, PLS, JPD, Cathepsin C, PALS
Target/Specificity Anti-DPPI recognizes recombinant protein DPPI.
Reconstitution & Storage Affinity purified
PrecautionsAnti-CTSC / Cathepsin C / JP Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name CTSC
Synonyms CPPI
Function Thiol protease (PubMed:1586157). Has dipeptidylpeptidase activity (PubMed:1586157). Active against a broad range of dipeptide substrates composed of both polar and hydrophobic amino acids (PubMed:1586157). Proline cannot occupy the P1 position and arginine cannot occupy the P2 position of the substrate (PubMed:1586157). Can act as both an exopeptidase and endopeptidase (PubMed:1586157). Activates serine proteases such as elastase, cathepsin G and granzymes A and B (PubMed:8428921).
Cellular Location Lysosome.
Tissue Location Ubiquitous. Highly expressed in lung, kidney and placenta. Detected at intermediate levels in colon, small intestine, spleen and pancreas.
Research Areas
Citations (0)
citation

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Discontinued
Cat# ALS17822
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