Anti-CTSC / Cathepsin C / JP Antibody
Mouse Anti Human Monoclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB, IHC-P, E |
---|---|
Primary Accession | P53634 |
Predicted | Human |
Host | Mouse |
Clonality | Monoclonal |
Isotype | IgG2b |
Calculated MW | 51854 Da |
Dilution | ELISA, IHC-P (1:50), WB (1:1000) |
Gene ID | 1075 |
---|---|
Alias Symbol | CTSC |
Other Names | CTSC, Cathepsin J, Dipeptidyl peptidase 1, Dipeptidyl peptidase I, DPP-I, Dipeptidyl transferase, Dipeptidyl-peptidase I, CPPI, DPPI, DPP1, HMS, JP, PDON1, PLS, JPD, Cathepsin C, PALS |
Target/Specificity | Anti-DPPI recognizes recombinant protein DPPI. |
Reconstitution & Storage | Affinity purified |
Precautions | Anti-CTSC / Cathepsin C / JP Antibody is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | CTSC |
---|---|
Synonyms | CPPI |
Function | Thiol protease (PubMed:1586157). Has dipeptidylpeptidase activity (PubMed:1586157). Active against a broad range of dipeptide substrates composed of both polar and hydrophobic amino acids (PubMed:1586157). Proline cannot occupy the P1 position and arginine cannot occupy the P2 position of the substrate (PubMed:1586157). Can act as both an exopeptidase and endopeptidase (PubMed:1586157). Activates serine proteases such as elastase, cathepsin G and granzymes A and B (PubMed:8428921). |
Cellular Location | Lysosome. |
Tissue Location | Ubiquitous. Highly expressed in lung, kidney and placenta. Detected at intermediate levels in colon, small intestine, spleen and pancreas. |
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