|Application ||WB, IHC-P, E|
|Calculated MW||51854 Da|
|Dilution||ELISA, IHC-P (1:50), WB (1:1000)|
|Other Names||CTSC, Cathepsin J, Dipeptidyl peptidase 1, Dipeptidyl peptidase I, DPP-I, Dipeptidyl transferase, Dipeptidyl-peptidase I, CPPI, DPPI, DPP1, HMS, JP, PDON1, PLS, JPD, Cathepsin C, PALS|
|Target/Specificity||Anti-DPPI recognizes recombinant protein DPPI.|
|Reconstitution & Storage||Affinity purified|
|Precautions||Anti-CTSC / Cathepsin C / JP Antibody is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Thiol protease. Has dipeptidylpeptidase activity. Active against a broad range of dipeptide substrates composed of both polar and hydrophobic amino acids. Proline cannot occupy the P1 position and arginine cannot occupy the P2 position of the substrate. Can act as both an exopeptidase and endopeptidase. Activates serine proteases such as elastase, cathepsin G and granzymes A and B. Can also activate neuraminidase and factor XIII.|
|Tissue Location||Ubiquitous. Highly expressed in lung, kidney and placenta. Detected at intermediate levels in colon, small intestine, spleen and pancreas.|
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