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Anti-DAP12 Antibody

Rabbit Anti Mouse Polyclonal Antibody

Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession O43914
Predicted Human, Mouse, Rat
Host Rabbit
Clonality Polyclonal
Isotype IgG
Calculated MW 12179 Da
Dilution IHC-P (5 µg/ml), WB (0.5 - 4 µg/ml)
Additional Information
Gene ID 7305
Alias Symbol TYROBP
Other Names TYROBP, DNAX-activation protein 12, DAP12, PLOSL, KARAP, KAR-associated protein, PLO-SL
Target/Specificity Recognizes mouse DAP-12. Species cross-reactivity: human, rat.
Reconstitution & Storage Immunoaffinity purified
PrecautionsAnti-DAP12 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Synonyms DAP12, KARAP
Function Non-covalently associates with activating receptors of the CD300 family. Cross-linking of CD300-TYROBP complexes results in cellular activation. Involved for instance in neutrophil activation mediated by integrin.
Cellular Location Membrane; Single-pass type I membrane protein
Tissue Location Expressed at low levels in the early development of the hematopoietic system and in the promonocytic stage and at high levels in mature monocytes. Expressed in hematological cells and tissues such as peripheral blood leukocytes and spleen. Also found in bone marrow, lymph nodes, placenta, lung and liver. Expressed at lower levels in different parts of the brain especially in the basal ganglia and corpus callosum.
Research Areas
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$ 450.00
Cat# ALS17824
(40 western blots)
Availability: 5 days
Bulk Size
Seasonal Special on Bulk Order
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