|Application ||WB, IHC-P, E|
|Calculated MW||43779 Da|
|Dilution||ELISA, IHC-P (10 µg/ml), WB|
|Other Names||SHBG, ABP, SBP, Sex hormone-binding globulin, Sex steroid-binding protein, TEBG|
|Reconstitution & Storage||Protein A purified|
|Precautions||Anti-SHBG Antibody (clone 5E6) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Functions as an androgen transport protein, but may also be involved in receptor mediated processes. Each dimer binds one molecule of steroid. Specific for 5-alpha-dihydrotestosterone, testosterone, and 17-beta-estradiol. Regulates the plasma metabolic clearance rate of steroid hormones by controlling their plasma concentration.|
|Cellular Location||Secreted. Note=In testis, it is synthesized by the Sertoli cells, secreted into the lumen of the seminiferous tubule and transported to the epididymis|
|Tissue Location||Isoform 1 and isoform 2 are present in liver and testis|
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