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Anti-PSMA7 Antibody (clone 1A10-3G12)

Mouse Anti Human Monoclonal Antibody

Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession O14818
Predicted Human
Host Mouse
Clonality Monoclonal
Isotype IgG2b,k
Clone Names 1A10-3G12
Calculated MW 27887 Da
Dilution ELISA, IF (1 - 10 µg/ml), IHC-P (20 µg/ml), IP, WB
Additional Information
Gene ID 5688
Alias Symbol PSMA7
Other Names PSMA7, Proteasome subunit RC6-1, XAPC7, Proteasome subunit alpha 4, Proteasome subunit XAPC7, RC6-1, HSPC
Target/Specificity Human PSMA7
Reconstitution & Storage Protein A purified
PrecautionsAnti-PSMA7 Antibody (clone 1A10-3G12) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name PSMA7
Synonyms HSPC
Function The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity. Plays an important role in the regulation of cell proliferation or cell cycle control, transcriptional regulation, immune and stress response, cell differentiation, and apoptosis. Interacts with some important proteins involved in transcription factor regulation, cell cycle transition, viral replication and even tumor initiation and progression. Inhibits the transactivation function of HIF-1A under both normoxic and hypoxia-mimicking conditions. The interaction with EMAP2 increases the proteasome-mediated HIF-1A degradation under the hypoxic conditions. Plays a role in hepatitis C virus internal ribosome entry site-mediated translation. Mediates nuclear translocation of the androgen receptor (AR) and thereby enhances androgen-mediated transactivation. Promotes MAVS degradation and thereby negatively regulates MAVS-mediated innate immune response.
Cellular Location Cytoplasm. Nucleus.
Research Areas
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$ 450.00
Cat# ALS17841
(40 western blots)
Availability: 5 days
Bulk Size
Seasonal Special on Bulk Order
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