|Application ||WB, IHC-P, E|
|Calculated MW||45057 Da|
|Dilution||ELISA, IHC-P (20 µg/ml), WB|
|Other Names||REN, Angiotensin-forming enzyme, Angiotensinogenase, HNFJ2, RENAA, Renin precursor, renal, Renin|
|Target/Specificity||Recognises amino acid residues 16-29 (MPSIRESLKERGVD) of the prosegment of prorenin.|
|Reconstitution & Storage||Protein G purified|
|Precautions||Anti-REN / Renin 1 Antibody (clone 6E2-B7) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Renin is a highly specific endopeptidase, whose only known function is to generate angiotensin I from angiotensinogen in the plasma, initiating a cascade of reactions that produce an elevation of blood pressure and increased sodium retention by the kidney.|
|Cellular Location||Secreted. Membrane. Note=Associated to membranes via binding to ATP6AP2|
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