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Anti-C5AR1 / CD88 / C5a Receptor Antibody

Rabbit Anti Human Polyclonal Antibody

Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P21730
Predicted Human
Host Rabbit
Clonality Polyclonal
Calculated MW 39336 Da
Dilution IHC-P (5 µg/ml), WB
Additional Information
Gene ID 728
Alias Symbol C5AR1
Other Names C5AR1, C5A, C5a-R, C5a ligand, C5a receptor, CD88, C5a anaphylatoxin receptor, C5AR, C5R1, CD88 antigen
Target/Specificity The antibody recognizes human complement C5a and its dimer form. Reactivity to other species has not been tested
Reconstitution & Storage Affinity purified
PrecautionsAnti-C5AR1 / CD88 / C5a Receptor Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name C5AR1
Synonyms C5AR, C5R1
Function Receptor for the chemotactic and inflammatory peptide anaphylatoxin C5a (PubMed:1847994, PubMed:8182049, PubMed:7622471, PubMed:9553099, PubMed:10636859, PubMed:15153520). The ligand interacts with at least two sites on the receptor: a high-affinity site on the extracellular N-terminus, and a second site in the transmembrane region which activates downstream signaling events (PubMed:8182049, PubMed:7622471, PubMed:9553099). Receptor activation stimulates chemotaxis, granule enzyme release, intracellular calcium release and superoxide anion production (PubMed:10636859, PubMed:15153520).
Cellular Location Cell membrane; Multi-pass membrane protein. Cytoplasmic vesicle. Note=Phosphorylated C5aR colocalizes with ARRB1 and ARRB2 in cytoplasmic vesicles
Research Areas
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$ 395.00
Cat# ALS17846
(40 western blots)
Availability: 5 days
Bulk Size
Seasonal Special on Bulk Order
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