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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   Anti-VHL / Von Hippel Lindau Antibody (aa167-179)   

Anti-VHL / Von Hippel Lindau Antibody (aa167-179)

Goat Anti Human Polyclonal Antibody

Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P40337
Predicted Human, Mouse, Rat, Rabbit, Monkey, Dog
Host Goat
Clonality Polyclonal
Calculated MW 24153 Da
Dilution ELISA (1:128000), IHC-P (5 µg/ml), WB (0.01 - 0.03 µg/ml)
Additional Information
Gene ID 7428
Alias Symbol VHL
Other Names VHL, Elongin binding protein, HRCA1, RCA1, VHL1, Von Hippel-Lindau syndrome, Protein G7, PVHL
Target/Specificity Human VHL. This antibody is expected to recognise both reported isoforms (NP_000542.1 and NP_937799.1).
Reconstitution & Storage Immunoaffinity purified
PrecautionsAnti-VHL / Von Hippel Lindau Antibody (aa167-179) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name VHL
Function Involved in the ubiquitination and subsequent proteasomal degradation via the von Hippel-Lindau ubiquitination complex. Seems to act as target recruitment subunit in the E3 ubiquitin ligase complex and recruits hydroxylated hypoxia- inducible factor (HIF) under normoxic conditions. Involved in transcriptional repression through interaction with HIF1A, HIF1AN and histone deacetylases. Ubiquitinates, in an oxygen-responsive manner, ADRB2.
Cellular Location Isoform 1: Cytoplasm. Membrane; Peripheral membrane protein. Nucleus. Note=Found predominantly in the cytoplasm and with less amounts nuclear or membrane-associated Colocalizes with ADRB2 at the cell membrane
Tissue Location Expressed in the adult and fetal brain and kidney
Research Areas
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$ 395.00
Cat# ALS17856
(40 western blots)
Availability: 5 days
Bulk Size
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