|Application ||IHC-P, E|
|Calculated MW||17394 Da|
|Dilution||ELISA (1:16000), IHC-P (5 µg/ml)|
|Other Names||HRASLS2, HRAS-like suppressor 2, PLA1/2-2|
|Target/Specificity||Human HRASLS2. This design was based on provisional sequence data.|
|Reconstitution & Storage||Immunoaffinity purified|
|Precautions||Anti-HRASLS2 Antibody (aa102-113) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Exhibits PLA1/2 activity, catalyzing the calcium- independent hydrolysis of acyl groups in various phosphatidylcholines (PC) and phosphatidylethanolamine (PE). For most substrates, PLA1 activity is much higher than PLA2 activity. Catalyzes N-acylation of PE using both sn-1 and sn-2 palmitoyl groups of PC as acyl donor. Also catalyzes O-acylation converting lyso-PC into PC.|
|Cellular Location||Cytoplasm. Membrane; Single-pass membrane protein. Note=Exhibits a granular pattern in the cytoplasm with preferential perinuclear localization|
|Tissue Location||Expressed in liver, kidney, small intestine testis and colon (PubMed:19615464). Undetectable in testis, placenta, salivary gland and fetal brain (PubMed:18163183)|
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