Anti-HMHA1 Antibody (aa57-71)
Goat Anti Human Polyclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| IHC-P, E |
---|---|
Primary Accession | Q92619 |
Predicted | Human, Hamster, Monkey, Bovine, Dog |
Host | Goat |
Clonality | Polyclonal |
Calculated MW | 124614 Da |
Dilution | ELISA (1:128000), IHC-P (5 µg/ml) |
Gene ID | 23526 |
---|---|
Alias Symbol | HMHA1 |
Other Names | HMHA1, ARHGAP45, HLA-HA1, Ha-1, KIAA0223, HA1 |
Target/Specificity | Human HMHA1 / HA-1. To avoid confusion please note that this antibody is designed to recognise the whole protein as coded by NP_036424.2 and will not recognise the peptide found eluted from HLA-A*0201 molecules by den Haan et al (Science. 1998 Feb 13 ... |
Reconstitution & Storage | Immunoaffinity purified |
Precautions | Anti-HMHA1 Antibody (aa57-71) is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | ARHGAP45 (HGNC:17102) |
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Function | Contains a GTPase activator for the Rho-type GTPases (RhoGAP) domain that would be able to negatively regulate the actin cytoskeleton as well as cell spreading. However, also contains N-terminally a BAR- domin which is able to play an autoinhibitory effect on this RhoGAP activity. |
Cellular Location | Cytoplasm. Cell projection, ruffle membrane |
Tissue Location | Expressed on cells of the hematopoietic lineage. Detected in dendritic cells and epidermal Langerhans cells. Expressed in peripheral blood mononuclear cells, in all leukemia/lymphoma cell lines. Detected also in some solid tumors and tissues such as cancerous and non-cancerous tissue. |
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