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Anti-MEX3C Antibody (aa541-554)

Goat Anti Human Polyclonal Antibody

Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q5U5Q3
Predicted Human, Mouse, Rabbit, Hamster, Pig, Bovine, Horse, Guinea Pig, Dog
Host Goat
Clonality Polyclonal
Calculated MW 69366 Da
Dilution ELISA (1:32000), IHC-P (5 µg/ml), WB (0.2 - 0.5 µg/ml)
Additional Information
Gene ID 51320
Alias Symbol MEX3C
Other Names MEX3C, RNF194, RING finger protein 194, RNA-binding protein MEX3C, BM-013, Mex-3 homolog C (C. elegans), MEX-3C, RKHD2
Target/Specificity Human MEX3C
Reconstitution & Storage Immunoaffinity purified
PrecautionsAnti-MEX3C Antibody (aa541-554) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name MEX3C
Synonyms RKHD2, RNF194
Function E3 ubiquitin ligase responsible for the post- transcriptional regulation of common HLA-A allotypes. Binds to the 3' UTR of HLA-A2 mRNA, and regulates its levels by promoting mRNA decay. RNA binding is sufficient to prevent translation, but ubiquitin ligase activity is required for mRNA degradation.
Cellular Location Cytoplasm. Nucleus. Note=Predominantly expressed in the cytoplasm and shuttles between the cytoplasm and the nucleus through the CRM1 export pathway. May act as suppressor of replication stress and chromosome missegregation
Tissue Location Highest levels found in fetal brain and testis. Also expressed in thymus, salivary gland and uterus Highly expressed in cells of the innate immune system, in particular activated NK cells. Week expression in the intestine
Research Areas
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$ 395.00
Cat# ALS17875
(40 western blots)
Availability: 5 days
Bulk Size
Seasonal Special on Bulk Order
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