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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   Anti-CIRP / CIRBP Antibody (clone 1C9)   

Anti-CIRP / CIRBP Antibody (clone 1C9)

Mouse Anti Human Monoclonal Antibody

Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q14011
Predicted Human
Host Mouse
Clonality Monoclonal
Isotype IgG2a,k
Clone Names 1C9
Calculated MW 18648 Da
Dilution ELISA, IF (10 µg/ml), IHC-P (10 µg/ml), WB
Additional Information
Gene ID 1153
Alias Symbol CIRBP
Other Names CIRBP, A18 hnRNP, A18HNRNP, CIRP
Target/Specificity Human CIRP / CIRBP
Reconstitution & Storage Protein A purified
PrecautionsAnti-CIRP / CIRBP Antibody (clone 1C9) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Synonyms A18HNRNP, CIRP
Function Cold-inducible mRNA binding protein that plays a protective role in the genotoxic stress response by stabilizing transcripts of genes involved in cell survival. Acts as a translational activator. Seems to play an essential role in cold- induced suppression of cell proliferation. Binds specifically to the 3'-untranslated regions (3'-UTRs) of stress-responsive transcripts RPA2 and TXN. Acts as a translational repressor (By similarity). Promotes assembly of stress granules (SGs), when overexpressed.
Cellular Location Nucleus, nucleoplasm. Cytoplasm. Note=Translocates from the nucleus to the cytoplasm after exposure to UV radiation. Translocates from the nucleus to the cytoplasm into stress granules upon various cytoplasmic stresses, such as osmotic and heat shocks. Its recruitment into stress granules occurs in the absence of TIAR proteins (By similarity).
Tissue Location Ubiquitous.
Research Areas
Citations (0)

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$ 450.00
Cat# ALS17886
(40 western blots)
Availability: 5 days
Bulk Size
Seasonal Special on Bulk Order
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