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Anti-POGZ Antibody (N-Terminus)
Rabbit Anti Mouse Polyclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, IHC-P, E |
|---|---|
| Primary Accession | Q7Z3K3 |
| Predicted | Human, Mouse, Rat, Chicken, Bovine, Dog |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Calculated MW | 155344 Da |
| Dilution | ELISA (1:100000 - 1:400000), IHC-P (5 µg/ml), WB (1:2000 - 1:20000) |
| Gene ID | 23126 |
|---|---|
| Alias Symbol | POGZ |
| Other Names | POGZ, KIAA0461, SUHW5, ZNF280E, Zinc finger protein 280E, ZNF635m, Zinc finger protein 635, ZNF635 |
| Target/Specificity | This antibody is known to react with mouse Pogz protein. A BLAST analysis was used to suggest cross-reactivity with Pogz from human, dog, short-tailed opossum, cattle, rat, chimpanzee, macaque, olive baboon, and chicken sources based on 100% homology ... |
| Reconstitution & Storage | Immunoaffinity purified |
| Precautions | Anti-POGZ Antibody (N-Terminus) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | POGZ |
|---|---|
| Synonyms | KIAA0461, SUHW5, ZNF280E, ZNF635 |
| Function | Plays a role in mitotic cell cycle progression and is involved in kinetochore assembly and mitotic sister chromatid cohesion. Probably through its association with CBX5 plays a role in mitotic chromosome segregation by regulating aurora kinase B/AURKB activation and AURKB and CBX5 dissociation from chromosome arms (PubMed:20562864). Promotes the repair of DNA double-strand breaks through the homologous recombination pathway (PubMed:26721387). |
| Cellular Location | Nucleus. Chromosome. Cytoplasm. Note=According to some authors, it is not localized to mitotic chromatin (PubMed:19244240). Recruited to trimethylated 'Lys-9' of histone H3 (H3K9me3) |
Research Areas
Citations (0)
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Application Protocols
Provided below are standard protocols that you may find useful for product applications.
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