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Anti-SUZ12 Antibody (clone 3D10)

Mouse Anti Human Monoclonal Antibody

Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q15022
Predicted Human
Host Mouse
Clonality Monoclonal
Isotype IgG1
Clone Names 3D10
Calculated MW 83055 Da
Dilution ELISA (1:10000), IHC-P (1:100), WB (1:500 - 1:2000)
Additional Information
Gene ID 23512
Alias Symbol SUZ12
Other Names SUZ12, ChET 9 protein, Joined to JAZF1 protein, CHET9, JJAZ1, KIAA0160, Polycomb protein SUZ12
Target/Specificity Human SUZ12
Reconstitution & Storage Ascites
PrecautionsAnti-SUZ12 Antibody (clone 3D10) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name SUZ12
Synonyms CHET9, JJAZ1, KIAA0160
Function Polycomb group (PcG) protein. Component of the PRC2/EED- EZH2 complex, which methylates 'Lys-9' (H3K9me) and 'Lys-27' (H3K27me) of histone H3, leading to transcriptional repression of the affected target gene. The PRC2/EED-EZH2 complex may also serve as a recruiting platform for DNA methyltransferases, thereby linking two epigenetic repression systems. Genes repressed by the PRC2/EED-EZH2 complex include HOXC8, HOXA9, MYT1 and CDKN2A.
Cellular Location Nucleus.
Tissue Location Overexpressed in breast and colon cancer.
Research Areas
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$ 395.00
Cat# ALS17894
(40 western blots)
Availability: 5 days
Bulk Size
Seasonal Special on Bulk Order
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