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Anti-GOK / STIM1 Antibody (N-Terminus)

Rabbit Anti Human Polyclonal Antibody

Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q13586
Predicted Human
Host Rabbit
Clonality Polyclonal
Calculated MW 77423 Da
Dilution ELISA (1:10000), IHC-P (5 µg/ml), WB (1 µg/ml)
Additional Information
Gene ID 6786
Alias Symbol STIM1
Other Names STIM1, D11S4896E, Stromal interaction molecule 1, GOK, STIM1L
Target/Specificity BLAST analysis suggests cross-reactivity with rat, bovine, and mouse based on 100% sequence homology.
Reconstitution & Storage Immunoaffinity purified
PrecautionsAnti-GOK / STIM1 Antibody (N-Terminus) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name STIM1
Synonyms GOK
Function Plays a role in mediating store-operated Ca(2+) entry (SOCE), a Ca(2+) influx following depletion of intracellular Ca(2+) stores. Acts as Ca(2+) sensor in the endoplasmic reticulum via its EF-hand domain. Upon Ca(2+) depletion, translocates from the endoplasmic reticulum to the plasma membrane where it activates the Ca(2+) release-activated Ca(2+) (CRAC) channel subunit, TMEM142A/ORAI1.
Cellular Location Cell membrane; Single-pass type I membrane protein. Endoplasmic reticulum membrane; Single-pass type I membrane protein. Cytoplasm, cytoskeleton. Note=Translocates from the endoplasmic reticulum to the cell membrane in response to a depletion of intracellular calcium and is detected at punctae corresponding to junctions between the endoplasmic reticulum and the cell membrane. Associated with the microtubule network at the growing distal tip of microtubules
Tissue Location Ubiquitously expressed in various human primary cells and tumor cell lines.
Research Areas
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$ 395.00
Cat# ALS17897
(40 western blots)
Availability: 5 days
Bulk Size
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