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Anti-TNFRSF1A / TNFR1 Antibody (aa20-43)

Rabbit Anti Mouse Polyclonal Antibody

     
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, IHC-P, IP
Primary Accession P19438
Predicted Human, Mouse, Rat, Rabbit, Monkey, Bovine, Dog
Host Rabbit
Clonality Polyclonal
Calculated MW 50495 Da
Dilution IHC-P (5 µg/ml), IP, WB (1:1000)
Additional Information
Gene ID 7132
Alias Symbol TNFRSF1A
Other Names TNFRSF1A, CD120a, CD120a antigen, MS5, p60, TBP1, TNF-R55, TNFAR, TNFR1, p55-R, TNF-R, TNF-R-I, TNF-R1, TNF-RI, Tnfr, TNFR-I, TNFR1-d2, TNFR60, FPF, p55, Tbpi, TNFR55
Target/Specificity Identifies a band ~55kD on WB.
Reconstitution & Storage Immunoaffinity purified
PrecautionsAnti-TNFRSF1A / TNFR1 Antibody (aa20-43) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name TNFRSF1A
Synonyms TNFAR, TNFR1
Function Receptor for TNFSF2/TNF-alpha and homotrimeric TNFSF1/lymphotoxin-alpha. The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis. Contributes to the induction of non-cytocidal TNF effects including anti-viral state and activation of the acid sphingomyelinase.
Cellular Location Cell membrane; Single-pass type I membrane protein Golgi apparatus membrane; Single-pass type I membrane protein. Secreted. Note=A secreted form is produced through proteolytic processing
Research Areas
Citations (0)
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Discontinued
Cat# ALS17898
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