|Application ||WB, IHC-P, E|
|Calculated MW||83284 Da|
|Dilution||ELISA, IHC-P (10 µg/ml), WB|
|Other Names||PIGR, Poly-Ig receptor|
|Reconstitution & Storage||Protein A purified|
|Precautions||Anti-PIGR Antibody (clone 2G5) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||This receptor binds polymeric IgA and IgM at the basolateral surface of epithelial cells. The complex is then transported across the cell to be secreted at the apical surface. During this process a cleavage occurs that separates the extracellular (known as the secretory component) from the transmembrane segment.|
|Cellular Location||Cell membrane; Single-pass type I membrane protein|
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