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Anti-PRMT7 Antibody (aa327-340)

Goat Anti Human Polyclonal Antibody

     
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, IHC-P, E
Primary Accession Q9NVM4
Predicted Human, Mouse, Monkey
Host Goat
Clonality Polyclonal
Calculated MW 78459 Da
Dilution ELISA (1:128000), IHC-P (5 µg/ml), WB (0.3 - 1 µg/ml)
Additional Information
Gene ID 54496
Alias Symbol PRMT7
Other Names PRMT7, KIAA1933
Target/Specificity Human PRMT7. This antibody is expected to recognize both reported isoforms (NP_061896.1; NP_001171753.1).
Reconstitution & Storage Immunoaffinity purified
PrecautionsAnti-PRMT7 Antibody (aa327-340) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name PRMT7
Synonyms KIAA1933
Function Arginine methyltransferase that can both catalyze the formation of omega-N monomethylarginine (MMA) and symmetrical dimethylarginine (sDMA), with a preference for the formation of MMA. Specifically mediates the symmetrical dimethylation of arginine residues in the small nuclear ribonucleoproteins Sm D1 (SNRPD1) and Sm D3 (SNRPD3); such methylation being required for the assembly and biogenesis of snRNP core particles. Specifically mediates the symmetric dimethylation of histone H4 'Arg-3' to form H4R3me2s. Plays a role in gene imprinting by being recruited by CTCFL at the H19 imprinted control region (ICR) and methylating histone H4 to form H4R3me2s, possibly leading to recruit DNA methyltransferases at these sites. May also play a role in embryonic stem cell (ESC) pluripotency. Also able to mediate the arginine methylation of histone H2A and myelin basic protein (MBP) in vitro; the relevance of such results is however unclear in vivo.
Cellular Location Cytoplasm, cytosol. Nucleus
Research Areas
Citations (0)
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Discontinued
Cat# ALS17913
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